GNx - Giatros Nutrition Dr. Ecdysterone 60 Caps

Νόμιμο συμπλήρωμα διατροφής με αριθμό γνωστοποίησης ΕΟΦ 121449/14-10-2025

DIRECTIONS OF USE.
Take 1 capsule (50 mg) in the morning after breakfast and 1 capsule (50 mg) at night after dinner.

ΔΙΑΤΡΟΦΙΚΑ ΣΤΟΙΧΕΙΑ.
Serving Size: 1 Capsule (2 Doses per Day)
Servings per Container: 30

	2 Caps	% NRV
Ecdysterone	100mg	**
* NRV = Nutrient Reference Value (EU Regulation 1169/2011). ** NRV not established.

Ecdysterone by Giatros Nutrition (GNx)

Ecdysterone (20-Hydroxyecdysone) is a naturally occurring phytoecdysteroid long recognized for its unique ability to enhance muscle growth, strength, and recovery without affecting hormonal balance. Unlike anabolic steroids, Ecdysterone acts through non-androgenic molecular pathways, primarily via estrogen receptor-β (ERβ) activation and mTOR signaling, resulting in improved muscle protein synthesis, cellular energy efficiency, and training adaptation. This mechanism allows for anabolic benefits comparable to traditional ergogenic compounds — but with complete endocrine safety and no suppression of natural hormones.

Scientifically Proven Benefits

In a double-blind, randomized study in trained men, supplementation with ecdysterone up to 50 mg daily for 10 weeks led to significantly greater increases in lean muscle mass and maximal strength (1RM bench press) compared to placebo, with no adverse effects. Mechanistic analysis demonstrated activation of the mTOR pathway and ERβ receptor, confirming ecdysterone’s ability to stimulate muscle protein synthesis and promote hypertrophy beyond placebo levels.

In a 12-week, double-blind, placebo-controlled study in adults over 50, administration of standardized spinach extract (a natural source of ecdysterone) significantly improved muscle strength and physical performance compared to placebo, confirming its efficacy in middle-aged and older individuals.

In a recent Phase 2b clinical trial, supplementation with 20-hydroxyecdysone (175–350 mg twice daily for 6–9 months) improved walking speed and lower-limb function in elderly individuals with sarcopenia, with a safety and tolerability profile identical to placebo. This large-scale study provides robust human evidence confirming functional improvement in muscle tissue and the excellent mid- to long-term safety of ecdysterone.

Earlier studies also showed that athletes taking Ecdisten (20-hydroxyecdysone) experienced increases in strength, muscle mass, and reductions in subcutaneous fat within just three weeks of training — particularly when combined with a high-protein diet. These early findings anticipated modern evidence supporting the ergogenic, non-hormonal anabolic properties of ecdysteroids.

Ecdysterone does not increase testosterone, DHT, or estrogen levels, nor does it suppress the body’s natural hormone production. It is classified as a natural, non-steroidal anabolic compound that acts through receptor-mediated intracellular signaling rather than hormonal conversion.

In summary, Giatros Nutrition Ecdysterone represents one of the most advanced natural anabolic supplements ever developed. It redefines what is possible in natural muscle optimization and performance science — the safest, cleanest, and most effective path to maximum strength, lean mass, and vitality.

References

- Isenmann E, Ambrosio G, Joseph JF, Mazzarino M, de la Torre X, Zimmer P, Kazlauskas R, Goebel C, Botrè F, Diel P, Parr MK. Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. Arch Toxicol. 2019 Jul;93(7):1807-1816. doi: 10.1007/s00204-019-02490-x. Epub 2019 May 23. PMID: 31123801.
- Pérez-Piñero S, Ávila-Gandía V, Rubio Arias JA, Muñoz-Carrillo JC, Losada-Zafrilla P, López-Román FJ. A 12-Week Randomized Double-Blind Placebo-Controlled Clinical Trial, Evaluating the Effect of Supplementation with a Spinach Extract on Skeletal Muscle Fitness in Adults Older Than 50 Years of Age. Nutrients. 2021 Dec 6;13(12):4373. doi: 10.3390/nu13124373. PMID: 34959924; PMCID: PMC8706266.
- Gadzhieva RM, Portugalov SN, Paniushkin VV, Kondrat'eva II. Sravnitel'noe izuchenie anaboliziruiushchego deĭstviia preparatov rastitel'nogo proiskhozhdeniia ékdistena, levetona i "Praĭm Plas" [A comparative study of the anabolic action of ecdysten, leveton and Prime Plus, preparations of plant origin]. Eksp Klin Farmakol. 1995 Sep-Oct;58(5):46-8. Russian. PMID: 8704590.
- Fielding RA, Dao MM, Cannon K, Desvarieux M, Miller SS, Gimness MP, Brandon DM, Villareal DT, Bruyere O, Bautmans I, Rickner K, Perry R, Kritchevsky SB, Musi N, Chehade JM, Kirstein JL, Gielen E, Pickrell P, Dilda P, Lafont R, Margalef C, Rolland Y, Del Signore S, Mariani J, Agus S, Tourette C, Dioh W, van Maanen R, Veillet S. BIO101 in Sarcopenic Seniors at Risk of Mobility Disability: Results of a Double-Blind Randomised Interventional Phase 2b Trial. J Cachexia Sarcopenia Muscle. 2025 Apr;16(2):e13750. doi: 10.1002/jcsm.13750. PMID: 40026058; PMCID: PMC11873539.
- Simakin SY, et al. The Combined Use of Ecdisten and the Product "Bodrost" during Training in Cyclical Types of Sport. Scientific Sports Bulletin. 1988;2.