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GNx - Giatros Nutrition - Dr. PureCut Zero 120 Caps

GNx - Giatros Nutrition - Dr. PureCut Zero 120 Caps
GNx - Giatros Nutrition - Dr. PureCut Zero 120 Caps
GNx - Giatros Nutrition - Dr. PureCut Zero 120 Caps
54.90€
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Product Details

Νόμιμο συμπλήρωμα διατροφής με αριθμό γνωστοποίησης ΕΟΦ 142970/21-11-2025

DIRECTIONS OF USE.
Take 2 capsules twice daily with food, or as directed by your physician or pharmacist.

SUPPLEMENT FACTS.
Serving Size: 2 Capsules (2 Doses per Day)
Servings per Container: 30
4 Caps% NRV
Sinetrol® X-Pur (Citrus Extract)900mg**
Grains of Paradise (Standardized Extract)40mg**
EGCG (from Green Tea Extract)400mg**
Synephrine (from Citrus aurantium)30mg**
Forskolin (from Coleus forskohlii)500mg**
Sunflower Lecithin80mg**
Capsaicin (from Cayenne Extract)8mg**
* NRV = Nutrient Reference Value (EU Regulation 1169/2011).
** NRV not established.

Dr. PureCut Zero by Giatros Nutrition (GNx)

Dr. PureCut Zero is a scientifically formulated thermogenic fat burner designed to activate the body’s natural fat-burning mechanisms. With clinically supported ingredients, it increases fat oxidation, enhances brown adipose tissue activity, and supports energy production.

Also ideal as a pre-workout, Dr. ThermoCut boosts energy and focus during high-intensity training. Dr. PureCut Zero συμβάλλει στην καύση λίπους με επιστημονικά τεκμηριωμένο τρόπο.

Sinetrol. Is a citrus extract standardized in hesperidin, naringin, and other bioactive polyphenols. It enhances fat metabolism by inhibiting PDE-4, thereby increasing cAMP similar to caffeine, but without stimulant side effects. Unlike synthetic stimulants, Sinetrol’s antioxidant profile also supports oxidative balance. Multiple clinical trials show that Sinetrol significantly reduces abdominal fat, waist circumference, and BMI.

Grains of Paradise.Activates TRPV1 and TRPA1 receptors, which stimulate brown adipose tissue (BAT)  a metabolically active fat depot specialized in thermogenesis. BAT dissipates energy as heat through UCP1-driven uncoupling, increasing basal energy expenditure and contributing to visceral fat loss. A 2022 RCT confirmed its ability to enhance BAT activity and reduce fat mass in healthy humans.

EGCG.Is the most bioactive catechin in green tea and acts by inhibiting catechol-O-methyltransferase (COMT), the enzyme that degrades norepinephrine. This prolongs the lipolytic effects of sympathetic neurotransmission. EGCG also activates AMP-activated protein kinase (AMPK), enhancing fat oxidation at rest and during exercise. It provides additional antioxidant and anti-inflammatory support. Evidence suggests its benefits extend to populations with polycystic ovary syndrome. Its fat-burning and weight-loss effects are supported by clinical research.

Synephrine.Is a selective b3-adrenergic receptor agonist, promoting lipolysis and thermogenesis with minimal stimulation of b1/b2 receptors (and therefore minimal cardiovascular strain). It reinforces the sympathetic fat-burning pathway and is especially effective in enhancing fat oxidation at FatMax exercise intensities. Its efficacy and cardiovascular safety is backed up by published studies.

Forskolin.Directly activates adenylate cyclase, increasing cAMP independently of adrenergic signaling. This promotes lipolysis via HSL and may also help preserve lean mass. Its non-stimulant mechanism makes it a unique and strategic addition to any thermogenic blend, backed up by evidence.

Capsaicin.Activates TRPV1 receptors, triggering sympathetic nervous system stimulation, catecholamine release, and thermogenesis. It supports diet-induced thermogenesis, may modestly suppress appetite, and enhances the effects of other thermogenic compounds.

Phospholipids: Phospholipids act as carriers and absorption enhancers, forming liposomal or micellar complexes with bioactive compounds. Through this mechanism, they improve the solubility of ingredients in lipid environments, enhance cell membrane permeability, and increase their bioavailability. Unlike substances such as piperine, they do not affect enzymatic systems (e.g., CYP450) or transport proteins, but act through physicochemical protection and transport of molecules, preventing their degradation in the gastrointestinal tract. This provides a safety advantage, as they present no risk of pharmacokinetic interactions.

References

- Dallas C, Gerbi A, Tenca G, Juchaux F, Bernard FX. Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE). Phytomedicine. 2008 Oct;15(10):783-92. doi: 10.1016/j.phymed.2008.05.006.
- Cases J, Romain C, Dallas C, Gerbi A, Rouanet JM. A 12-week randomized double-blind parallel pilot trial of Sinetrol XPur on body weight, abdominal fat, waist circumference, and muscle metabolism in overweight men. Int J Food Sci Nutr. 2015;66(4):471-7. doi: 10.3109/09637486.2015.1042847.
- Cases J, Romain C, Dallas C, Gerbi A, Rouanet JM. A 12-week randomized double-blind parallel pilot trial of Sinetrol XPur on body weight, abdominal fat, waist circumference, and muscle metabolism in overweight men. Int J Food Sci Nutr. 2015;66(4):471-7. doi: 10.3109/09637486.2015.1042847.
- Sudeep HV, Aman K, Jestin TV, Shyamprasad K. Aframomum melegueta Seed Extract with Standardized Content of 6-Paradol Reduces Visceral Fat and Enhances Energy Expenditure in Overweight Adults - A Randomized Double-Blind, Placebo-Controlled Clinical Study. Drug Des Devel Ther. 2022 Oct 28;16:3777-3791. doi: 10.2147/DDDT.S367350.
- Vázquez Cisneros LC, López-Uriarte P, López-Espinoza A, Navarro Meza M, Espinoza-Gallardo AC, Guzmán Aburto MB. Efectos del té verde y su contenido de galato de epigalocatequina (EGCG) sobre el peso corporal y la masa grasa en humanos. Una revisión sistemática. Nutr Hosp. 2017 Jun 5;34(3):731-737. doi: 10.20960/nh.753.
- Yang CS, Zhang J, Zhang L, Huang J, Wang Y. Mechanisms of body weight reduction and metabolic syndrome alleviation by tea. Mol Nutr Food Res. 2016 Jan;60(1):160-74. doi: 10.1002/mnfr.201500428.
- Hursel R, Viechtbauer W, Westerterp-Plantenga MS. The effects of green tea on weight loss and weight maintenance: a meta-analysis. Int J Obes (Lond). 2009 Sep;33(9):956-61. doi: 10.1038/ijo.2009.135.
- Gholami F, Antonio J, Iranpour M, Curtis J, Pereira F. Does green tea catechin enhance weight-loss effect of exercise training in overweight and obese individuals? J Int Soc Sports Nutr. 2024 Dec;21(1):2411029. doi: 10.1080/15502783.2024.2411029.
- Colonetti L, Grande AJ, Toreti IR, Ceretta LB, da Rosa MI, Colonetti T. Green tea promotes weight loss in women with polycystic ovary syndrome: Systematic review and meta-analysis. Nutr Res. 2022 Aug;104:1-9. doi: 10.1016/j.nutres.2022.03.009.
- Gutiérrez-Hellín J, Ruiz-Moreno C, Del Coso J. Acute p-synephrine ingestion increases whole-body fat oxidation during 1-h of cycling at Fatmax. Eur J Nutr. 2020 Oct;59(7):3341-3345. doi: 10.1007/s00394-019-02101-6.
- Gutiérrez-Hellín J, Del Coso J. Dose-Response Effects of p-Synephrine on Fat Oxidation Rate During Exercise of Increasing Intensity. Phytother Res. 2018 Feb;32(2):370-374. doi: 10.1002/ptr.5937.
- Ruiz-Moreno C, Del Coso J, Giráldez-Costas V, González-García J, Gutiérrez-Hellín J. Effects of p-Synephrine during Exercise: A Brief Narrative Review. Nutrients. 2021 Jan 15;13(1):233. doi: 10.3390/nu13010233.
- Stohs SJ, Preuss HG, Keith SC, Keith PL, Miller H, Kaats GR. Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. Int J Med Sci. 2011 Apr 28;8(4):295-301. doi: 10.7150/ijms.8.295.
- Shara M, Stohs SJ, Mukattash TL. Cardiovascular Safety of Oral p-Synephrine (Bitter Orange) in Healthy Subjects: A Randomized Placebo-Controlled Cross-over Clinical Trial. Phytother Res. 2016 May;30(5):842-7. doi: 10.1002/ptr.5590.
- Godard MP, Johnson BA, Richmond SR. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obes Res. 2005 Aug;13(8):1335-43. doi: 10.1038/oby.2005.162.
- Lejeune MP, Kovacs EM, Westerterp-Plantenga MS. Effect of capsaicin on substrate oxidation and weight maintenance after modest body-weight loss in human subjects. Br J Nutr. 2003 Sep;90(3):651-59. doi: 10.1079/bjn2003938.