GNx - Giatros Nutrition Dr. BrainFuel - Advanced Brain Support 180 Caps

Νόμιμο συμπλήρωμα διατροφής με αριθμό γνωστοποίησης ΕΟΦ 156330/18-12-2025

DIRECTIONS OF USE.
Take 3 capsules, 2 times a day (morning and evening), with or without food, or according to the instructions of your doctor or pharmacist.

SUPPLEMENT FACTS.
Serving Size: 3 Capsules | Servings per Container: 30

	6 Capsules	% NRV
Lion’s Mane Mushroom	1000mg	**
Citicoline (CDP-Choline)	500mg	**
Bacopa Monnieri Extract	600mg	**
L-Tyrosine	1000mg	**
Caffeine Anhydrous	200mg	**
Rhodiola Rosea Extract	99mg	**
* NRV = Nutrient Reference Value (EU Regulation 1169/2011). ** NRV not established.

Dr. BrainFuel by Giatros Nutrition (GNx)

The BrainFuel by GIATROS NUTRITION is a scientifically-formulated nootropic designed to enhance physical and mental energy, short-term memory, processing speed, neurotransmitter balance, and stress resilience. It contains clinically validated ingredients that support dopaminergic and cholinergic pathways, promote neuroplasticity, and regulate cortisol and fatigue — without overstimulation. — Whether you're looking for more energy at the gym, preparing for exams, managing demanding projects, or simply trying to combat chronic fatigue, Dr. BrainFuel offers a strategic, science-based advantage for your mind and body.

The Lion’s Mane is a neurotrophic mushroom shown to stimulate the expression of nerve growth factor (NGF) in the brain. NGF supports neurite outgrowth, myelination, and long-term synaptic plasticity — essential for learning, memory consolidation, and repair of damaged neurons. Lion’s Mane has been associated with improvements in mild cognitive impairment, mental clarity, and mood stability in both animal models and human trials.

Η Citicoline is a highly bioavailable form of choline that crosses the blood–brain barrier and acts as a precursor to acetylcholine — the key neurotransmitter involved in focus, learning, and muscle activation. It also promotes the synthesis of phosphatidylcholine, a critical component of neuronal membranes, thereby supporting membrane integrity and mitochondrial function. Clinical studies have demonstrated that citicoline may improve attention, memory recall, executive function, motivation, and even mood.

Η Bacopa monnieri is a traditional Ayurvedic nootropic shown to enhance synaptic transmission, improve working memory, and increase learning speed through bacosides that modulate cholinergic signaling and serotonin turnover. It also possesses antioxidant and adaptogenic properties, reducing oxidative stress and protecting neurons from glutamate-induced toxicity. Clinical studies have demonstrated improved verbal recall, reaction time, and cognitive processing in both young adults and older populations.

Η L-Tyrosine is a non-essential amino acid and precursor to dopamine, norepinephrine, and epinephrine. Under cognitive stress or sleep deprivation, catecholamine depletion impairs memory and focus. Supplementing with L-Tyrosine restores catecholaminergic tone, preserving working memory, vigilance, and multitasking performance during stress. It is particularly beneficial for individuals under mental load, burnout, or shift work

Η Caffeine is a central nervous system stimulant that acts by antagonizing adenosine receptors, leading to increased dopamine and norepinephrine release. The result is enhanced alertness, focus, and both physical and mental energy. At moderate doses, caffeine improves reaction time, short-term memory, and motivation — especially when combined with adaptogens. The 100 mg of caffeine per dose in Dr. BrainFuel, equivalent to a cup of coffee, delivers its benefits without excessive nervousness or overstimulation.

Η Rhodiola rosea is a potent adaptogen known for its ability to modulate the stress response and regulate cortisol levels. It enhances the transmission of key monoamines such as dopamine and serotonin, contributing to improved mood, focus, and resilience against mental fatigue. Its active constituents, rosavin and salidroside, have been clinically shown to boost energy, cognitive performance, physical performance and strength as well as emotional well-being in individuals exposed to psychological or physical stress.

References

- Olsson EM, von Schéele B, Panossian AG. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009 Feb;75(2):105-12. doi: 10.1055/s-0028-1088346.

- Docherty S, Doughty FL, Smith EF. The Acute and Chronic Effects of Lion's Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study. Nutrients. 2023 Nov 20;15(22):4842. doi: 10.3390/nu15224842.

- La Monica MB, Raub B, Ziegenfuss EJ, Hartshorn S, Grdic J, Gustat A, Sandrock J, Ziegenfuss TN. Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion's Mane Extracts on Cognitive Performance. Nutrients. 2023 Dec 6;15(24):5018. doi: 10.3390/nu15245018.

- Contato AG, Conte-Junior CA. Lion's Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential-A Narrative Review. Nutrients. 2025 Apr 9;17(8):1307. doi: 10.3390/nu17081307.

- Bonvicini M, Travaglini S, Lelli D, Antonelli Incalzi R, Pedone C. Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-Analysis. Nutrients. 2023 Jan 12;15(2):386. doi: 10.3390/nu15020386.

- Nakazaki E, Mah E, Sanoshy K, Citrolo D, Watanabe F. Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutr. 2021 Aug 7;151(8):2153-2160. doi: 10.1093/jn/nxab119.

- McGlade E, Agoston AM, DiMuzio J, Kizaki M, Nakazaki E, Kamiya T, Yurgelun-Todd D. The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males. J Atten Disord. 2019 Jan;23(2):121-134. doi: 10.1177/1087054715593633.

- Roohi-Azizi M, Arabzadeh S, Amidfar M, Salimi S, Zarindast MR, Talaei A, Akhondzadeh S. Citicoline Combination Therapy for Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial. Clin Neuropharmacol. 2017 Jan/Feb;40(1):1-5. doi: 10.1097/WNF.0000000000000185.

- Pham HTN, Phan SV, Tran HN, et al. Bacopa monnieri (L.) Ameliorates Cognitive Deficits Caused in a Trimethyltin-Induced Neurotoxicity Model Mice. Biol Pharm Bull. 2019;42(8):1384-1393. doi: 10.1248/bpb.b19-00288.

- Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, Limpeanchob N, Norman Scholfield C. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol. 2014;151(1):528-35. doi: 10.1016/j.jep.2013.11.008.

- Fatima U, Roy S, Ahmad S, et al. Pharmacological attributes ofBacopa monnieriextract: Current updates and clinical manifestation. Front Nutr. 2022 Aug 18;9:972379. doi: 10.3389/fnut.2022.972379.

- Calabrese C, Gregory WL, Leo M, Kraemer D, Bone K, Oken B. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. J Altern Complement Med. 2008 Jul;14(6):707-13. doi: 10.1089/acm.2008.0018.

- Valotto Neto LJ, Reverete de Araujo M, Moretti Junior RC, et al. Investigating the Neuroprotective and Cognitive-Enhancing Effects ofBacopa monnieri: A Systematic Review Focused on Inflammation, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis. Antioxidants (Basel). 2024 Mar 25;13(4):393. doi: 10.3390/antiox13040393.

- Hase A, Jung SE, aan het Rot M. Behavioral and cognitive effects of tyrosine intake in healthy human adults. Pharmacol Biochem Behav. 2015 Jun;133:1-6. doi: 10.1016/j.pbb.2015.03.008.

- Jongkees BJ, Hommel B, Kühn S, Colzato LS. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review. J Psychiatr Res. 2015 Nov;70:50-7. doi: 10.1016/j.jpsychires.2015.08.014. Epub 2015 Aug 25.

- Lorenzo Calvo J, Fei X, Domínguez R, Pareja-Galeano H. Caffeine and Cognitive Functions in Sports: A Systematic Review and Meta-Analysis. Nutrients. 2021 Mar 6;13(3):868. doi: 10.3390/nu13030868.

- Marcos-Frutos D, Leban Ž, Li Z, Zhang X, Lara PM, Alix-Fages C, Jiménez-Martínez P, Zebboudji N, Caillet A, Redondo B, Vera J, Janicijevic D, García-Ramos A. The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial. Nutrients. 2025 Mar 7;17(6):940. doi: 10.3390/nu17060940.

- Liao YH, Chao YC, Sim BY, Lin HM, Chen MT, Chen CY. Rhodiola/Cordyceps-Based Herbal Supplement Promotes Endurance Training-Improved Body Composition But Not Oxidative Stress and Metabolic Biomarkers: A Preliminary Randomized Controlled Study. Nutrients. 2019 Oct 3;11(10):2357. doi: 10.3390/nu11102357.

- Lekomtseva Y, Zhukova I, Wacker A. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial. Complement Med Res. 2017;24(1):46-52. doi: 10.1159/000457918.